ANTI-HISTAMINES CLASSIFICATION

 ANTI-HISTAMINES CLASSIFICATION

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Histamine is a Autocoid(Means it is a local hormon); Auto= Self & Coid=Akos(Healing substance)

                                            It is a organic nitrogenous compound which involves in immunological responds and also having many pharmacological role in body. 

CLASSIFICATION OF H1-RECEPTOR ANTAGONIST/ANTI-HISTAMINES

[I]FIRST GENERATION ANT-IHISTAMINES(CLASSICAL ANTI-HISTAMINES)

1.Aminoalkyl ethers (Ethanolamines):-

eg: Diphenhydramine HCL, Dimenhydrinate, doxylamine succinate, Clemostine Fumarate, Diphenyl Pyraline HCL

2.Ethylene diamines:-

eg: Tripelennamine HCL

3. Piperazines(Cyclidines):-

eg: Chlorocyclizine HCL, Meclizine HCL, Buclizine HCL

4. Propylamines(Monoamino Propyl derivatives):-

eg: Pheniramine maleate, Chlorpheniramine Maleate, Triprolidine HCL, Phenindamine tartarate

5.Phenothiazines:-

eg: Promethazine, Trimeprazine tartarate

6.Dibenzocycloheptenes & Dibenzocycloheptanes:-

eg: Cyproheptadine, azatadine Maleate

[II] SECOND GENERATION ANTI-HISTAMINES(NON-SEDATIVE ANTI-HISTAMINES)

eg: Cetrizine, Fexofenadine HCL, Loratadine, Astemizole, levo-cetrizine

[III] MAST CELL STABILIZER

Inhibit the release of histamine from mast cell

eg: Cromolyn Sodium 

CLASSIFICATION OF H2-RECEPTOR ANTAGONIST

eg: Cimetidine, Famotidine, Ranitidine